What are the side effects of high dose of caffeine?
Long term consumption of high dose of caffeine can lead to insomnia, anxiety, mood disorders, premature ejaculation and other dysfunctions. Too much caffeine would increase the secretion of ACTH, which is the hormone that triggers the adrenal glands to produce lots stress hormones. High dose of coffeine has been shown to cause premature ejaculation due to the hyper-stimulation of the prostate and affect the parasympathetic nerves.
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